plot_clint: Plot Mass Spectrometry Responses from Measurements of...

In invitroTKstats: In Vitro Toxicokinetic Data Processing and Analysis Pipeline

Plot Mass Spectrometry Responses from Measurements of Intrinsic Hepatic Clearance

Description

This function generates a response-versus-time plot of mass spectrometry (MS) responses collected from measurements of intrinsic hepatic clearance for a chemical. Responses from different measurements/calibrations are labeled with different colors, and responses from various sample types are labeled with different shapes.

Usage

plot_clint(level2, dtxsid, color.palette = "viridis")

Arguments

level2	(Data Frame) A data frame containing level-2 data with a measure of chemical clearance over time when incubated with suspended hepatocytes.
dtxsid	(Character) EPA's DSSTox Structure ID for the chemical to be plotted.
color.palette	(Character) A character string indicating which viridis R package color map option to use. (Defaults to "viridis".)

Details

The function requires "level-2" data for plotting. Level-2 data is level-1, data formatted with the format_clint function, and curated with a verification column. "Y" in the verification column indicates the data row is valid for plotting.

Value

ggplot2

A figure of mass spectrometry responses over time for various sample types.

Author(s)

John Wambaugh

Examples

## Load example level-2 data 
level2 <- invitroTKstats::clint_L2
plot_clint(level2, dtxsid = "DTXSID1021116")

invitroTKstats documentation built on Aug. 23, 2025, 9:08 a.m.