Metabolomic Quantitative Trait Locus mapping

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Description

mQTL provides a complete QTL analysis pipeline for 1H NMR data. Distinctive features include normalisation using QPN approach, peak alignment using RSPA approach, dimensionality reduction using SRV approach and finally QTL mapping using R/qtl package.

Details

Package: mQTL
Type: Package
Version: 1.0
Date: 2013-09-18
License: GPL (>= 3)

Main fucntions:

  • format_mQTL: creates the proper format of data

  • align_mQTL: peak alignment and normalisation

  • pre_mQTL: dimension reduction by statistical recoupling of variables

  • process_mQTL: computes LODs using extended Haley-Knott method

  • post_mQTL: plots the results of a given run

  • summary_mQTL: provides the results as a table

Author(s)

Lyamine Hedjazi and Jean-Baptiste Cazier

Maintainer: Lyamine Hedjazi <l.hedjazi@fondation-ican.com>