Description Usage Arguments Details Value Author(s) References See Also Examples
Function to process the tissue extract of the individuals for QTL analysis
1 | process_mQTL(datfile, genfile, nperm = 0)
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datfile |
phenotype data |
genfile |
genotype data |
nperm |
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This function makes use of metabolomic and genotype data to perform QTL analysis based on the R/QTL package, for mapping quantitative trait loci. In particular, it makes use of the extended Haley-Knott method to optimize the LOD score evaluation and avoid problems with missing genotypes.
2D LOD score table
Jean-Baptiste Cazier and Hedjazi Lyamine
Broman,K., et al (2006) R/qtl: QTL mapping in experimental crosses, Bioinformatics, 19(7), 889-890.
1 2 3 4 5 6 7 8 | ## Not run:
## Pre-process data
infile<-"ReducedData.dat" ## Reduced data by SRV
cleangen<-"CleanGenoFile.dat" ## Genotype data file in csvs format
nperm <- 0 ## Number of permutations
MQTL_results<-process_mQTL(infile, cleangen, nperm))
## End(Not run)
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