normalise: Normalisation of metabolomic data

Description Usage Arguments Value Author(s) References See Also Examples

Description

Removing dilutions between biofluid samples (normalisation of spectra)

Usage

1
normalise(X, method)

Arguments

X

metabolomic data

method

total area (method<-"total") or quotient probabilistic method (method<-"prob")

Value

normalised spectrum

Author(s)

Lyamine Hedjazi

References

Dieterle,F., et al (2006) Probabilistic Quotient Normalization as Robust Method to Account for Dilution of Complex Biological Mixtures. Application in 1H NMR Metabonomics, Anal. Chem., 78(13), 42814290.

See Also

SRV

Examples

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## Data
Sp=matrix(rnorm(10*13454,mean=0,sd=1), nrow=10,ncol=13454)

## Quotient probabilistic normalisation
NormDat<-normalise(abs(Sp),'prob')


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