normalise: Normalisation of metabolomic data

In mQTL: Metabolomic Quantitative Trait Locus Mapping

Description

Removing dilutions between biofluid samples (normalisation of spectra)

Usage

normalise(X, method)

Arguments

X	metabolomic data
method	total area (method<-"total") or quotient probabilistic method (method<-"prob")

Value

normalised spectrum

Author(s)

Lyamine Hedjazi

References

Dieterle,F., et al (2006) Probabilistic Quotient Normalization as Robust Method to Account for Dilution of Complex Biological Mixtures. Application in 1H NMR Metabonomics, Anal. Chem., 78(13), 42814290.

See Also

SRV

Examples

## Data
Sp=matrix(rnorm(10*13454,mean=0,sd=1), nrow=10,ncol=13454)

## Quotient probabilistic normalisation
NormDat<-normalise(abs(Sp),'prob')

mQTL documentation built on May 1, 2019, 7:30 p.m.