genetic-mapping-functions | R Documentation |
These functions facilitate the conversion between recombination fractions (r) and genetic distances (d) using various mapping models. The functions starting with 'mf_' convert recombination fractions to genetic distances, while those starting with 'imf_' convert genetic distances back into recombination fractions.
mf_k(d)
mf_h(d)
mf_m(d)
imf_k(r)
imf_h(r)
imf_m(r)
d |
Numeric or numeric vector, representing genetic distances in centiMorgans (cM) for direct functions (mf_k, mf_h, mf_m). |
r |
Numeric or numeric vector, representing recombination fractions for inverse functions (imf_k, imf_h, imf_m). |
The 'mf_' prefixed functions apply different models to convert recombination fractions into genetic distances:
mf_k
: Kosambi mapping function.
mf_h
: Haldane mapping function.
mf_m
: Morgan mapping function.
The 'imf_' prefixed functions convert genetic distances back into recombination fractions:
imf_k
: Inverse Kosambi mapping function.
imf_h
: Inverse Haldane mapping function.
imf_m
: Inverse Morgan mapping function.
Kosambi, D.D. (1944). The estimation of map distances from recombination values. Ann Eugen., 12, 172-175. Haldane, J.B.S. (1919). The combination of linkage values, and the calculation of distances between the loci of linked factors. J Genet, 8, 299-309. Morgan, T.H. (1911). Random segregation versus coupling in Mendelian inheritance. Science, 34(873), 384.
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