genetic-mapping-functions: Genetic Mapping Functions

genetic-mapping-functionsR Documentation

Genetic Mapping Functions

Description

These functions facilitate the conversion between recombination fractions (r) and genetic distances (d) using various mapping models. The functions starting with 'mf_' convert recombination fractions to genetic distances, while those starting with 'imf_' convert genetic distances back into recombination fractions.

Usage

mf_k(d)

mf_h(d)

mf_m(d)

imf_k(r)

imf_h(r)

imf_m(r)

Arguments

d

Numeric or numeric vector, representing genetic distances in centiMorgans (cM) for direct functions (mf_k, mf_h, mf_m).

r

Numeric or numeric vector, representing recombination fractions for inverse functions (imf_k, imf_h, imf_m).

Details

The 'mf_' prefixed functions apply different models to convert recombination fractions into genetic distances:

  • mf_k: Kosambi mapping function.

  • mf_h: Haldane mapping function.

  • mf_m: Morgan mapping function.

The 'imf_' prefixed functions convert genetic distances back into recombination fractions:

  • imf_k: Inverse Kosambi mapping function.

  • imf_h: Inverse Haldane mapping function.

  • imf_m: Inverse Morgan mapping function.

References

Kosambi, D.D. (1944). The estimation of map distances from recombination values. Ann Eugen., 12, 172-175. Haldane, J.B.S. (1919). The combination of linkage values, and the calculation of distances between the loci of linked factors. J Genet, 8, 299-309. Morgan, T.H. (1911). Random segregation versus coupling in Mendelian inheritance. Science, 34(873), 384.


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