convert_from_vcf: Converting VCF data files into PLINK v1.9 and PLINK v2.0 data...

In plinkQC: Genotype Quality Control with 'PLINK'

Converting VCF data files into PLINK v1.9 and PLINK v2.0 data files

Description

This converts files in the VCF format (i.e. name.vcf) into PLINK v1.9 format (i.e. name.bed, name.bim, and name.fam) and/or PLINK v2.0 format (i.e. name.pvar, name.psam, and name.pgen)

Usage

convert_from_vcf(
  indir,
  name,
  qcdir = indir,
  verbose = FALSE,
  path2plink2 = NULL,
  gzipped = FALSE,
  makebed = TRUE,
  makepgen = FALSE,
  showPlinkOutput = TRUE
)

Arguments

indir	[character] /path/to/directory containing the basic vcf file, name.vcf or name.vcf.gz
name	[character] Prefix of VCF files, i.e. name.vcf or name.vcf.gz
qcdir	[character] /path/to/directory where the plink1.9 or plink2 data formations as returned by plink2 –vcf –make-bed or plink2 –vcf –make-pgen will be saved to. User needs writing permission to qcdir. Per default is qcdir=indir.
verbose	[logical] If TRUE, progress info is printed to standard out.
path2plink2	[character] Absolute path to PLINK executable (https://www.cog-genomics.org/plink/2.0/) i.e. plink 2 should be accessible as path2plink -h. The full name of the executable should be specified: for windows OS, this means path/plink.exe, for unix platforms this is path/plink. If not provided, assumed that PATH set-up works and PLINK will be found by exec('plink').
gzipped	[logical] Put as TRUE if the vcf file is gzipped (i.e. name.vcf.gz)
makebed	[logical] If TRUE, will output PLINK v1.9 files (i.e. name.bed, name.bim, and name.fam)
makepgen	[logical] If TRUE, will output PLINK v2.0 files (i.e. name.pvar, name.psam, and name.pgen)
showPlinkOutput	[logical] If TRUE, plink log and error messages are printed to standard out.

Value

Creates PLINK v1.9 or PLINK v2.0 datafiles

Examples

indir <- system.file("extdata", package="plinkQC")
qcdir <- tempdir()
name <- "data"
path2plink <- '/path/to/plink'
## Not run: 
# the following code is not run on package build, as the path2plink on the
# user system is not known.
convert_to_plink2(indir=indir, qcdir=qcdir, name=name, path2plink2 = path2plink2)

## End(Not run)

plinkQC documentation built on March 27, 2026, 5:07 p.m.