imbal: Representing the allocation imbalance

In randomizeR: Randomization for Clinical Trials

Representing the allocation imbalance

Description

Represents the imbalance of the treatment assignments of patients in a clinical trial.

Usage

imbal(type)

Arguments

type	character string, should be one of "imb", "absImb", "loss", or "maxImb", see Details.

Details

Balance of the treatment assignment of patients can be an issue in the design of a clinical trial. The imbal function is a constructor function for an S4 object of class imbal representing the issue of imbalance of a clinical trial. The parameter type can take the following values: The type

"imb"

the final imbalance, i.e. difference in group sizes at the end of a trial

"absImb"

the absolute value of the final imbalance

"loss"

the loss in power estimation, i.e. imb^2/N

"maxImb"

the maximal attained imbalance during the trial

Value

S4 object of class imbal, a formal representation of the issue of imbalance in a clinical trial.

References

A.C. Atkinson (2014) Selecting a biased coin design. Statistical Science, 29, Vol. 1, 144-163.

See Also

Other issues: chronBias, combineBias(), corGuess, issue, selBias, setPower()

randomizeR documentation built on Sept. 19, 2023, 1:08 a.m.