Description Usage Arguments Value
Function for calculating LOQ
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MRD |
The measured MRD values |
input_cancer_cells |
The pre-specified input. Note: can be frequency or any other input value |
conf.level |
Confidence level for calculating upper and lower bounds, default 0.95 |
log |
Boolean for log10-transforming input_cancer_cells, default TRUE |
log_offset |
log offset for transformation to avoid log(0), default 1e-6 |
TE.plot |
If TRUE, returns a ggplot of the Total Error fit |
sadler_params |
A list of initial values for sadler's fit |
extra_sadler_log |
Whether to take an extra log to improve Sadler fit stability; i.e.: log(y) ~ log(b1+b2*x)^b3) |
prob |
Detection probability for LOD, default 0.95 |
Returns a list containing LOQ, LCL.LOQ and UCL.LOQ. Note that LCL.LOQ will almost always be NA; use LOD as the lower limit. If TE.plot == TRUE, also contains TE_fit, fitted_data and TE_plot.
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