README.md

In GHLCLab/phexpo: Bidirectional enrichment analysis of phenotypes and chemicals

Phexpo

Phexpo is an R package for enrichment analysis of phenotypes (from the Human Phenotype Ontology(Köhler et al., 2019)) and chemicals (from the Comparative Toxicogenomics Database(Davis et al., 2019)).

Human Phenotype Ontology Citation:

This service/product is using the Human Phenotype Ontology (2019-02-12). Find out more at http://www.human-phenotype-ontology.org

Comparative Toxicogenomics Database Citation:

Curated [chemical–gene interactions] data were retrieved from the Comparative Toxicogenomics Database (CTD), MDI Biological Laboratory, Salisbury Cove, Maine, and NC State University, Raleigh, North Carolina. World Wide Web (URL: http://ctdbase.org/). [February, 2019]. Curated [chemical vocabulary] data were retrieved from the Comparative Toxicogenomics Database (CTD), MDI Biological Laboratory, Salisbury Cove, Maine, and NC State University, Raleigh, North Carolina. World Wide Web (URL: http://ctdbase.org/). [February, 2019].

References

Davis,A.P. et al. (2019) The Comparative Toxicogenomics Database: update 2019. Nucleic Acids Res., 47, D948–D954. Köhler,S. et al. (2019) Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources. Nucleic Acids Res., 47, D1018–D1027.

GHLCLab/phexpo documentation built on Jan. 9, 2020, 12:10 a.m.