chem2gene: Chemical and gene interactions

Description Usage Format Details

Description

Dataset of chemicals and their gene interactions. Original dataset downloaded on 11-Feb-2019. Version Feb-05-2019. Dataset has been filtered to contain only the organisms Homo sapiens, Mus musculus, Rattus norvegicus, Rattus rattus, Danio rerio, Macaca fascicularis, Macaca mulatta and human gene IDs. Genes were checked that they belonged to humans using the Homo sapien gene info from National Center for Biotechnology Information (NCBI) (downloaded 19-March-2019). For gene IDs not belonging to Homo sapiens, gene IDs were checked that they belonged to their respective organism using All Mammalia gene info from NCBI (15-March-2019) and Danio rerio gene info from NCBI (15-March-2019). All orthologues for these gene IDs were found using NCBI Homologene (version 06-May-2014) and outdated orthologue gene IDs were updated to the latest gene ID using NCBI gene_history (15-March-2019) and updated gene symbols were retrieved from Homo sapien gene info. Tibble, dplyr, readr, tidyr, magrittr and annotationTools were used in the generation of this dataset.

Usage

1

Format

An object of class tbl_df (inherits from tbl, data.frame) with 1575035 rows and 11 columns.

Details

@format A tibble data frame of 1,575,035 rows and 11 columns.

@source http://ctdbase.org/downloads/#cg


GHLCLab/phexpo documentation built on Jan. 9, 2020, 12:10 a.m.