perfFishTestHPOMultiple: Chemical enrichment for multiple phenotype terms

In GHLCLab/phexpo: Bidirectional enrichment analysis of phenotypes and chemicals

Description

Chemical enrichment for multiple phenotype terms

Usage

perfFishTestHPOMultiple(HPO, enrich_1S = TRUE)

Arguments

HPO	List of Human Phenotype Ontology terms characters
enrich_1S	Enrichment one-sided. Default set to true for enrichment, where the one-sided Fisher's exact is set to alternative = "greater." If enrich_1S = FALSE, Fisher's exact is set to alternative = "two.sided" for two.sided.

Value

Tibble data frame with enrichment.

Note

Chemical enrichment for multiple HPO terms is a simplistic exploratory function, where we take an additive approach. HPO terms used should be phenotypic abnormality terms within the HPO release 2019-02-12.

Examples

perfFishTestHPOMultiple(list("Increased circulating ACTH level",
"Androgen insufficiency",
"Decreased circulating aldosterone level"))

GHLCLab/phexpo documentation built on Jan. 9, 2020, 12:10 a.m.