mouse2human_eset: Converting mouse gene symbol to human gene symbol of...

In IOBR/IOBR: Immune Oncology Biological Research

Converting mouse gene symbol to human gene symbol of expression set.

Description

This function converts mouse gene symbols to human gene symbols in an expression dataset. It supports using either an online resource (Ensembl) or a local dataset for conversion.

Usage

mouse2human_eset(
  eset,
  source = "ensembl",
  is_matrix = TRUE,
  column_of_symbol = NULL,
  verbose = FALSE
)

Arguments

eset	expression matrix or data frame
source	default is ensembl, if an error is reported, set parameter to 'local' and mus_human_gene_symbol will be use to convert gene symbols
is_matrix	Boolean indicating if 'eset' is a matrix; defaults to TRUE. If FALSE, 'column_of_symbol' must be specified.
column_of_symbol	default is null.Name of the column in 'eset' that contains gene symbols, if 'eset' is not a matrix. This parameter must be specified if 'is_matrix' is FALSE.

Value

Returns the expression set with human gene symbols for further analysis.

Examples

# Set the number of rows and columns
num_rows <- 200
num_cols <- 10

# Generate sample names and mouse gene symbols
sample_names <- paste0("Sample", 1:num_cols)
mouse_genes <- paste0("MouseGene", 1:num_rows)

# Create random data for the data frame
data <- matrix(runif(num_rows * num_cols), nrow = num_rows, ncol = num_cols)
df <- data

rownames(df) <- anno_gc_vm32$symbol[1:200]
human_data <- mouse2human_eset(df, source = "local", is_matrix = TRUE)

IOBR/IOBR documentation built on July 16, 2025, 8:12 p.m.