get_ceRNA: Find Specific ceRNA (Gene)

Description Usage Arguments Value Examples

View source: R/specific_ceRNA.R

Description

Get all ceRNAs in a disease of interest (search not for a specific ceRNA, but search for all ceRNAs satisfying filter functions).

Usage

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get_ceRNA(
  disease_name,
  ensg_number = NULL,
  gene_symbol = NULL,
  gene_type = NULL,
  minBetweenness = NULL,
  minNodeDegree = NULL,
  minEigenvector = NULL,
  sorting = NULL,
  descending = TRUE,
  limit = 100,
  offset = NULL
)

Arguments

disease_name

Name of the specific cancer type/dataset. If default is set, all available datasets with corresponding informations are shown. Fuzzy search available.

ensg_number

A vector of ensg number(s). If ensg number is set, gene symbol and gene type must be NULL. One of the three identifiers must be provided.

gene_symbol

A vector of gene symbol(s). If gene symbol is set, ensg number and gene type must be NULL. One of the three identifiers must be provided.

gene_type

Defines the type of gene of interest. One out of [3prime_overlapping_ncRNA, antisense, antisense_RNA, bidirectional_promoter_lncRNA, IG_C_gene, IG_C_pseudogene, IG_V_gene, IG_V_pseudogene, lincRNA, macro_lncRNA, miRNA, misc_RNA, Mt_rRNA, polymorphic_pseudogene, processed_pseudogene, processed_transcript, protein_coding, pseudogene, ribozyme, rRNA, rRNA_pseudogene, scaRNA, scRNA, sense_intronic, sense_overlapping, snoRNA, snRNA, TEC, TR_C_gene, TR_V_gene, TR_V_pseudogene, transcribed_processed_pseudogene, transcribed_unitary_pseudogene, transcribed_unprocessed_pseudogene, translated_processed_pseudogene, unitary_pseudogene, unprocessed_pseudogene, vaultRNA].

minBetweenness

Threshold of the betweenness.

minNodeDegree

Threshold of the degree.

minEigenvector

Threshold of the eigenvektor.

sorting

Possibilities for sorting of the results. Possible values are "degree", "betweenness" or "eigenvector".

descending

Descending (TRUE, default) or ascending (FALSE) ordering of the results.

limit

Number of results that should be shown. Default value is 100 and can be up to 1000. For more results please use batches, the provided offset parameter or download the whole dataset.

offset

Starting point from where results should be shown.

Value

A data_frame containing all ceRNAs (genes) satisfying the given filters.

Examples

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get_ceRNA(disease_name = "kidney clear cell carcinoma",
          gene_type = "lincRNA", minBetweenness = 0.8)

IceQueen1996/spongeAPI documentation built on March 8, 2021, 8:33 p.m.