get_specific_miRNAInteraction: miRNA Induced ceRNA Interaction

In IceQueen1996/spongeAPI: User Friendly Application Of The SPONGE API

Description

Get all ceRNA interactions where miRNA(s) of interest (different identifiers available - e.g. hs number or mimat number) contribute to.

Usage

get_specific_miRNAInteraction(
  disease_name = NULL,
  mimat_number = NULL,
  hs_number = NULL,
  pValue = 0.05,
  pValueDirection = "<",
  mscor = NULL,
  mscorDirection = "<",
  correlation = NULL,
  correlationDirection = "<",
  limit = 100,
  offset = NULL
)

Arguments

disease_name	Name of the specific cancer type/dataset. If default is set, all available datasets with corresponding informations are shown. Fuzzy search available.
mimat_number	Mimat_number of interest. If mimat_number is set, hs_number must be NULL.
hs_number	hs_number of interest. If hs_number is set, mimat_number must be NULL.
pValue	Threshold of the FDR adjusted p-value. Default is 0.05.
pValueDirection	Direction of the FDR adjusted p-value threshold (<, >). Must be set if pValue is set. Possible values are: "<", ">".
mscor	Threshold of the 'multiple sensitivity correlation' (mscor).
mscorDirection	Direction of the mscor threshold (<, >). Must be set if pValue is set. Possible values are: "<", ">".
correlation	Threshold of the correlation.
correlationDirection	Direction of the correlation threshold (<, >). Must be set if pValue is set. Possible values are: "<", ">".
limit	Number of results that should be shown. Default value is 100 and can be up to 1000. For more results please use batches, the provided offset parameter or download the whole dataset.
offset	Starting point from where results should be shown.

Value

A data_frame containing all ceRNA interactions fitting the parameters.

Examples

# Retrieve all possible ceRNA interactions where miRNA of interest contribute to
get_specific_miRNAInteraction(disease_name = "kidney clear cell carcinoma",
                              mimat_number = "MIMAT0000076",
                              limit = 15)
## Not run: 
# Do not use both possible identifiers at once
get_specific_miRNAInteraction(disease_name = "kidney clear cell carcinoma",
                              mimat_number ="MIMAT0000076",
                              hs_number = "hsa-miR-21-5p",
                              limit = 15)

## End(Not run)

IceQueen1996/spongeAPI documentation built on March 8, 2021, 8:33 p.m.