DNBcompute_custom.default: Compute the Dynamic Network Biomarkers(DNB) model with...

In Kaiyu-W/DNBr: Compute the Dynamic Network Biomarkers (DNB) model

Compute the Dynamic Network Biomarkers(DNB) model with customized Modules

Description

Compute the Dynamic Network Biomarkers(DNB) model with customized Modules

Usage

## Default S3 method:
DNBcompute_custom(
  data,
  module_list,
  meta,
  meta_levels = NULL,
  force_allgene = TRUE,
  size_effect = TRUE,
  quiet = FALSE,
  ...
)

Arguments

data	the gene expression matrix, which can be a single-cell RNA-seq GEM with at least three group/clusters or a matrix merging bulk GEMs from at least three different sample
module_list	a customized list of module gene
meta	a data.frame with rownames as cell-id as well as one column of group infomation
meta_levels	the order of meta group, default ordered by decreasing if NULL
force_allgene	not use
size_effect	whether consider the effect of sample size when compute CI of DNB, default TRUE
quiet	do not message
...	not use

Value

S3:DNB_output

Kaiyu-W/DNBr documentation built on April 27, 2024, 10:09 a.m.