allThreshes | defines the thresholds to be used for tree building |
calcSubcloneProportions | Calculate proportions of subclones in each sample (assumes... |
calcTreeScores | Calculate SCHISM fitness scores for trees |
calculateTreeScoreMutations | Calculate SCHISM fitness scores for trees |
collectBestKChains | Collect chains for best K of each mutation set |
colorScheme | generate colors for each vertice |
enumerateSpanningTreesModified | Enumerate all spanning trees using modified Gabow-Myers |
estimateClusterAssignments | Determine most probable mutation cluster assignments by... |
estimateICN | Determine most probable integer assignments by taking those... |
estimateMCFs | Determine the most probable cluster MCF values by taking the... |
estimateMultiplicity | Determine most probable mutation cluster assignments by... |
filterEdgesBasedOnCCFs | Filter possible edges based on lineage precedence |
generateAllTrees | Enumerate all spanning trees using modified Gabow-Myers... |
importFiles | read input data file and store in required format |
importMutationFileOnly | import mutation file |
mcmcMain | run PICTograph in an automated pipeline |
mergeSetChains | Relabel chains for all sets and merge |
pictograph-package | pictograph |
plotAllTrees | Plot all trees with the highest scores |
plotChainsMCF | Plot CCF chain trace |
plotClusterAssignmentProbVertical | Plot probabilities of mutation cluster assignments - vertical |
plotEnsembleTree | Plot ensemble tree |
plotMCFViolin | Plot cluster CCF posterior distributions as violin plots |
plotSubcloneBar | Plot subclone proportions in each sample as stacked bar chart |
plotSubclonePie | Plot pie charts for subclone proportions in each sample |
plotTree | Plot single tree |
prepareGraph | Create tibble of possible edges from CCF values based on... |
runMCMCForAllBoxes | run MCMC using JAGS |
separateMutationsBySamplePresence | sample presence for MCMC |
writeClusterAssignmentsTable | Determine most probable mutation cluster assignments by... |
writeClusterMCFsTable | Determine the most probable cluster MCF values by taking the... |
writeIcnTable | Determine most probable integer copy number by taking those... |
writeMultiplicityTable | Determine most probable multiplicity assignments by taking... |
writeSetKTable | Make table listing possible choices of K (minimum BIC and... |
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