Man pages for KarchinLab/pictograph
Tools for modeling clonal evolution of a cancer

allThreshesdefines the thresholds to be used for tree building
calcSubcloneProportionsCalculate proportions of subclones in each sample (assumes...
calcTreeScoresCalculate SCHISM fitness scores for trees
calculateTreeScoreMutationsCalculate SCHISM fitness scores for trees
collectBestKChainsCollect chains for best K of each mutation set
colorSchemegenerate colors for each vertice
enumerateSpanningTreesModifiedEnumerate all spanning trees using modified Gabow-Myers
estimateClusterAssignmentsDetermine most probable mutation cluster assignments by...
estimateICNDetermine most probable integer assignments by taking those...
estimateMCFsDetermine the most probable cluster MCF values by taking the...
estimateMultiplicityDetermine most probable mutation cluster assignments by...
filterEdgesBasedOnCCFsFilter possible edges based on lineage precedence
generateAllTreesEnumerate all spanning trees using modified Gabow-Myers...
importFilesread input data file and store in required format
importMutationFileOnlyimport mutation file
mcmcMainrun PICTograph in an automated pipeline
mergeSetChainsRelabel chains for all sets and merge
pictograph-packagepictograph
plotAllTreesPlot all trees with the highest scores
plotChainsMCFPlot CCF chain trace
plotClusterAssignmentProbVerticalPlot probabilities of mutation cluster assignments - vertical
plotEnsembleTreePlot ensemble tree
plotMCFViolinPlot cluster CCF posterior distributions as violin plots
plotSubcloneBarPlot subclone proportions in each sample as stacked bar chart
plotSubclonePiePlot pie charts for subclone proportions in each sample
plotTreePlot single tree
prepareGraphCreate tibble of possible edges from CCF values based on...
runMCMCForAllBoxesrun MCMC using JAGS
separateMutationsBySamplePresencesample presence for MCMC
writeClusterAssignmentsTableDetermine most probable mutation cluster assignments by...
writeClusterMCFsTableDetermine the most probable cluster MCF values by taking the...
writeIcnTableDetermine most probable integer copy number by taking those...
writeMultiplicityTableDetermine most probable multiplicity assignments by taking...
writeSetKTableMake table listing possible choices of K (minimum BIC and...
KarchinLab/pictograph documentation built on Oct. 25, 2024, 10:10 a.m.