mr_egger_regression: Egger's regression for Mendelian randomization

In MRCIEU/TwoSampleMR: Two Sample MR Functions and Interface to MR Base Database

Egger's regression for Mendelian randomization

Description

Egger's regression for Mendelian randomization

Usage

mr_egger_regression(b_exp, b_out, se_exp, se_out, parameters)

Arguments

b_exp	Vector of genetic effects on exposure.
b_out	Vector of genetic effects on outcome.
se_exp	Standard errors of genetic effects on exposure.
se_out	Standard errors of genetic effects on outcome.
parameters	List of parameters.

Value

List of with the following elements:

b

MR estimate

se

Standard error of MR estimate

pval

p-value of MR estimate

b_i

Estimate of horizontal pleiotropy (intercept)

se_i

Standard error of intercept

pval_i

p-value of intercept

Q, Q_df, Q_pval

Heterogeneity stats

mod

Summary of regression

dat

Original data used for MR Egger regression

MRCIEU/TwoSampleMR documentation built on Sept. 28, 2024, 6:51 p.m.