mr_ivw: Inverse variance weighted regression

In MRCIEU/TwoSampleMR: Two Sample MR Functions and Interface to MR Base Database

Inverse variance weighted regression

Description

The default multiplicative random effects IVW estimate. The standard error is corrected for under dispersion Use the mr_ivw_mre() function for estimates that don't correct for under dispersion.

Usage

mr_ivw(b_exp, b_out, se_exp, se_out, parameters = default_parameters())

Arguments

b_exp	Vector of genetic effects on exposure.
b_out	Vector of genetic effects on outcome.
se_exp	Standard errors of genetic effects on exposure.
se_out	Standard errors of genetic effects on outcome.
parameters	List of parameters.

Value

List with the following elements:

b

MR estimate

se

Standard error

pval

p-value

Q, Q_df, Q_pval

Heterogeneity stats

MRCIEU/TwoSampleMR documentation built on Sept. 28, 2024, 6:51 p.m.