mr_simple_median: Simple median method

In MRCIEU/TwoSampleMR: Two Sample MR Functions and Interface to MR Base Database

Simple median method

Description

Perform MR using summary statistics. Bootstraps used to calculate standard error.

Usage

mr_simple_median(
  b_exp,
  b_out,
  se_exp,
  se_out,
  parameters = default_parameters()
)

Arguments

b_exp	Vector of genetic effects on exposure.
b_out	Vector of genetic effects on outcome.
se_exp	Standard errors of genetic effects on exposure.
se_out	Standard errors of genetic effects on outcome.
parameters	The number of bootstrap replications used to calculate the SE can be set through parameters=list(nboot = 1000). The default is list(nboot=1000).

Value

List with the following elements:

b

MR estimate

se

Standard error

pval

p-value

nsnp

The number of SNPs

MRCIEU/TwoSampleMR documentation built on Sept. 28, 2024, 6:51 p.m.