mr_weighted_median: Weighted median method

In MRCIEU/TwoSampleMR: Two Sample MR Functions and Interface to MR Base Database

Weighted median method

Description

Perform MR using summary statistics. Bootstraps used to calculate standard error.

Usage

mr_weighted_median(
  b_exp,
  b_out,
  se_exp,
  se_out,
  parameters = default_parameters()
)

Arguments

b_exp	Vector of genetic effects on exposure.
b_out	Vector of genetic effects on outcome.
se_exp	Standard errors of genetic effects on exposure.
se_out	Standard errors of genetic effects on outcome.
parameters	The default is default_parameters(). Specify the number of bootstrap replications to calculate the SE with nboot. The default is list(nboot=1000).

Value

List with the following elements:

b

MR estimate

se

Standard error

pval

p-value

MRCIEU/TwoSampleMR documentation built on April 22, 2024, 8:42 p.m.