PPTPResponseLevel: Define response level based on PPTP response criteria

Description Usage Arguments Details Value References See Also

View source: R/DRAP_code_1.5.11.r

Description

Define the drug response level of each animal based on the PPTP response criteria.

Usage

1

Arguments

data

a data frame of measured volume data.

criteria

the criteria used to defined response level.

Details

The 'Reference' for suitable condition of PPTP response criteria includes: 1. The initional tumor volume is between 200 and 500 mm3; 2. If the tumor volume readches to 4-fold of its initial volume, the mouse reaches endpoint; else the drug treatment lasts to 42 days.

Value

The response level of each animal.

References

Murphy, B., et al. Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis. Cancer Res 2016;76(19):5798-5809.

See Also

DRLevel, NPDXEResponseLevel, RCResponseLevel


SCBIT-YYLab/DRAP documentation built on April 7, 2020, 2:03 a.m.