plotDRResults: plot the results of drug response level analysis.

In SCBIT-YYLab/DRAP: Drug Response Analysis Tailored for Drug Testing on Patient-Derived Tumor Models

Description

Visulize the result of drug response analysis, such as RR or DCR of each arm.

Usage

plotDRResults(data, by, min.number, measurement = c('RR','DCR','both'), ...)

Arguments

data	drug response level ,the output of DRLevel.
by	the level summaried by.
min.number	the lower cutoff of sample number of every arm
measurement	the response evaluation indexes used, whether "RR", "DCR", or "both".
...	other parameters passed to ggplot

Examples

# NPDXE.criteria 
npdxe.criteria <- data.frame(BestResponse.lower = c(-1000,-0.95,-0.5,0.35),
                             BestResponse.upper = c(-0.95,-0.5,0.35,1000),
                             BestAvgResponse.lower = c(-1000,-0.4,-0.2,0.3), 
                             BestAvgResponse.upper = c(-0.4,-0.2,0.3,1000), 
                             Level = c( 'CR','PR', 'SD','PD'))
npdxe.criteria

data(TAN.volume.data)
TAN.drl <- DRLevel(data = TAN.volume.data, 
                   method = 'NPDXE.Response', 
                   criteria = npdxe.criteria, 
                   neg.control = 'Control')
plotDRResults(TAN.drl,by = 'Arms',measurement = 'DCR',min.number = 5)

SCBIT-YYLab/DRAP documentation built on April 7, 2020, 2:03 a.m.