SampleNMM: Normal-Uniform mixture model fitting

In Shicheng-Guo/CHAT: Clonal Heterogeneity Analysis Tool

Description

This function fits the distribution of a input vector with mixture of Normal and Uniform distributions and returns the BIC score for the model.

Usage

SampleNMM(Y)

Arguments

Y	input vector. In the context of subclonality inference, Y can either be sAGP or CCF values from one sample.

Details

The model is: Y~ A*U(0,1)+(1-A)*Normal(mu,sigma), where A, mu and sigma are parameters to be fitted.

Value

a list containing the following elements:

BIC	BIC score from the model.
fit	a vector containing three numbers, in the order of fitted A, mu and sigma.

Author(s)

Bo Li

Examples

Y=c(rnorm(100,0.5,0.3),runif(100,0,1))
SampleNMM(Y)

Shicheng-Guo/CHAT documentation built on Oct. 30, 2019, 11:55 p.m.