Description Usage Arguments Value Author(s) Examples
Using bi-modal Guassian fitting to calculate folded B-allele-frequency.
1 | getBAFmean(bb)
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bb |
numeric vector, original B-allele-frequency data from a given DNA segment. |
a numeric number for folded BAF estimate.
Bo Li
1 2 3 4 5 6 7 8 9 10 11 | ## generate BAF values symmetric around 0.5, resembling real data in a CNA region
y1<-rnorm(100,0.3,0.1)
y2<-rnorm(100,0.7,0.1)
y<-c(y1,y2)
## compute folded BAF
getBAFmean(y)
## generate BAF values distributed around 0.5, resembling real data in a non-CNA region
y<-rnorm(200,0.5,0.2)
## compute folded BAF
getBAFmean(y)
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