randomise_FC_weights: Randomise source:ligand and receptor:target weights

In VCCRI/scTalk: Single-cell talk - an R package for analysis of cell-cell communication networks from single-cell data.

Description

Generates a randomisation of the network by shuffling the source:ligand and receptor:target weights, which are dervied from fold-change expression. The ligand:receptor weights derived from STRINGdb remain unshuffled. The weights are then summed to represent randomised source:target path weights.

Usage

randomise_FC_weights(ppi.weights, cluster.ligand.table, receptor.cluster.table)

Arguments

ppi.weights	a vector of ligands
cluster.ligand.table	a vector of receptors
receptor.cluster.table	species to use - either mouse (default) or human

Value

a vector of source:target path weights

Examples

## Not run: 
RandomiseFCWeights(ppi.weights, cluster.ligand.table, receptor.cluster.table)

## End(Not run)

VCCRI/scTalk documentation built on June 5, 2021, 6:35 a.m.