Airpart identifies sets of genes displaying differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. It makes use of a generalized fused lasso with binomial observations of allelic counts to partition cell types by their allelic imbalance. Alternatively, a nonparametric method for partitioning cell types is offered. The package includes a number of visualizations and quality control functions for examining single cell allelic imbalance datasets.
Package details |
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| Bioconductor views | ATACSeq CellBiology ChIPSeq Clustering DifferentialExpression FunctionalGenomics GeneExpression GeneRegulation GraphAndNetwork QualityControl RNASeq Regression Sequencing SingleCell Transcription TranscriptomeVariant |
| Maintainer | |
| License | GPL-2 |
| Version | 1.7.1 |
| URL | https://github.com/Wancen/airpart |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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