BIC_BUS: Obtain BIC form the output by BUSgibbs

Description Usage Arguments Value Author(s) References Examples

Description

The BIC value can be used to determine the subtype number if it is unknown to the users.

Usage

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BIC_BUS(BUSfits)

Arguments

BUSfits

The BUSfits object from the function BUSgibbs.

Value

BIC_val

The BIC value for the BUS model with the subtype number being n.subtypes, the input subtype number for the BUSgibbs function that generates the BUSfits object.

Author(s)

Xiangyu Luo

References

Xiangyu Luo, Yingying Wei. Batch Effects Correction with Unknown Subtypes. Journal of the American Statistical Association. Accepted.

Examples

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rm(list = ls(all = TRUE))  
set.seed(123)
#a toy example, there are 6 samples and 20 genes in each batch
example_Data <- list()

#batch 1
example_Data[[1]] <- rbind(matrix(c(1,1,5,5,10,10,
						3,3,7,7,12,12), ncol=6, byrow=TRUE), matrix(c(1,2),nrow=18, ncol=6))

#batch 2
batch2_effect <- c(2,2,2,1,1)
example_Data[[2]] <- rbind(matrix(c(1,1,5,5,10,10,
						3,3,7,7,12,12), ncol=6, byrow=TRUE), matrix(c(1,2),nrow=18, ncol=6)) + batch2_effect

#batch 3
batch3_effect <- c(3,2,1,1,2)
example_Data[[3]] <- rbind(matrix(c(1,1,5,5,10,10,
						3,3,7,7,12,12), ncol=6, byrow=TRUE), matrix(c(1,2),nrow=18, ncol=6)) + batch3_effect

set.seed(123)
BUSfits <- BUSgibbs(example_Data, n.subtypes = 3, n.iterations = 100, showIteration = FALSE)
BIC_val <- BIC_BUS(BUSfits)

XiangyuLuo/BUScorrect documentation built on June 14, 2019, 3:31 p.m.