LNM.Simulation: Logistical Normal Multinomial Distribution Simulation

In ZRChao/LRTT: Differential Abundance Analysis for Microbiome data incorpating phylogeney

Usage

LNM.Sim(p, seed, N, dif)

Arguments

p	OTU numbers
seed	random seeds
N	sample size
dif	the differential OTU

Details

Return one count matrix of leaves and internal nodes which colnames corresponds to the tree.

Value

One count matrix

Author(s)

Chou ZHOU

References

Xia, Fan, et al. "A logistic normal multinomial regression model for microbiome compositional data analysis." Biometrics 69.4 (2013): 1053-1063.

Examples

p <- 10
dif <- c(2,3)

data <- LNM.Sim(p, seed =1, N =10 , dif)
dim(data)

OTU.dif <- data[, colnames(daya) == dif]
boxplot(OTU.dif[1:N, 1], OTU.dif[-c(1:N), 1])

ZRChao/LRTT documentation built on May 17, 2019, 6:36 p.m.