get_neighbors: Get 1st-order neighbors of a given gene or group of genes

View source: R/gcn_inference.R

get_neighborsR Documentation

Get 1st-order neighbors of a given gene or group of genes

Description

Get 1st-order neighbors of a given gene or group of genes

Usage

get_neighbors(genes, net, cor_threshold = 0.7)

Arguments

genes

Character vector containing genes from which direct neighbors will be extracted.

net

List object returned by exp2gcn.

cor_threshold

Correlation threshold to filter connections. As a weighted network is a fully connected graph, a cutoff must be selected. Default is 0.7.

Value

List containing 1st-order neighbors for each input gene.

Author(s)

Fabricio Almeida-Silva

See Also

exp2gcn SFT_fit

Examples

data(filt.se)
genes <- rownames(filt.se)[1:10]
gcn <- exp2gcn(filt.se, SFTpower = 18, cor_method = "pearson")
neighbors <- get_neighbors(genes, gcn)

almeidasilvaf/BioNERO documentation built on Oct. 9, 2024, 1:49 a.m.