get_neighbors: Get 1st-order neighbors of a given gene or group of genes

In almeidasilvaf/BioNERO: Biological Network Reconstruction Omnibus

Get 1st-order neighbors of a given gene or group of genes

Description

Get 1st-order neighbors of a given gene or group of genes

Usage

get_neighbors(genes, net, cor_threshold = 0.7)

Arguments

genes	Character vector containing genes from which direct neighbors will be extracted.
net	List object returned by exp2gcn.
cor_threshold	Correlation threshold to filter connections. As a weighted network is a fully connected graph, a cutoff must be selected. Default is 0.7.

Value

List containing 1st-order neighbors for each input gene.

Author(s)

Fabricio Almeida-Silva

See Also

exp2gcn SFT_fit

Examples

data(filt.se)
genes <- rownames(filt.se)[1:10]
gcn <- exp2gcn(filt.se, SFTpower = 18, cor_method = "pearson")
neighbors <- get_neighbors(genes, gcn)

almeidasilvaf/BioNERO documentation built on March 25, 2024, 9:14 p.m.