The aim of BPRMeth is to extract higher order features associated with the shape of methylation profiles across a defined genomic region. Using these higher order features across promoter-proximal regions, BPRMeth provides a powerful machine learning predictor of gene expression. Check the vignette on how to use the package.
To get the latest development version from Github:
# install.packages("devtools")
devtools::install_github("andreaskapou/BPRMeth-devel")
Kapourani, C.-A. and Sanguinetti, G. (2016). Higher order methylation features for clustering and prediction in epigenomic studies. Bioinformatics 32 (17), i405-i412. (Best Paper Award in ECCB 2016).
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