Description Usage Arguments Value
process_diff_haib_caltech is a wrapper method ...
| 1 2 3 4 5 | process_diff_haib_caltech(bs_contr_files, bs_treat_files, rna_contr_files,
  rna_treat_files, chrom_size_file = NULL, chr_discarded = NULL,
  upstream = -100, downstream = 100, min_bs_cov = 0, max_bs_cov = 1000,
  cpg_density = 1, sd_thresh = 0, ignore_strand = FALSE, fmin = -1,
  fmax = 1)
 | 
| bs_contr_files | The name of the control BS-Seq '.bed' formatted files to read data values from. | 
| bs_treat_files | The name of the treatment BS-Seq '.bed' formatted files to read data values from. | 
| rna_contr_files | The name of the control RNA-Seq '.bed' formatted files to read data values from. | 
| rna_treat_files | The name of the treatment RNA-Seq '.bed' formatted files to read data values from. | 
| chrom_size_file | Optional name of the file containing genome chromosome sizes | 
| chr_discarded | A vector with chromosome names to be discarded. | 
| upstream | Integer defining the length of bp upstream of TSS. | 
| downstream | Integer defining the length of bp downstream of TSS. | 
| min_bs_cov | The minimum number of reads mapping to each CpG site. | 
| max_bs_cov | The maximum number of reads mapping to each CpG site. | 
| cpg_density | Optional integer defining the minimum number of CpGs that
have to be in a methylated region. Regions with less than  | 
| sd_thresh | Optional numeric defining the minimum standard deviation of the methylation change in a region. This is used to filter regions with no methylation change. | 
| ignore_strand | Logical, whether or not to ignore strand information. | 
| fmin | Optional minimum range value for region location scaling. Under this version, this parameter should be left to its default value. | 
| fmax | Optional maximum range value for region location scaling. Under this version, this parameter should be left to its default value. | 
A diff_processHTS object which contains among others the
following information: 
methyl_region: A list
containing the methylation regions, where each each entry in the list
consists of an L X 3 dimensional matrix, where: 
1st col: Contains the locations of the CpGs relative to TSS, where the range (min, max) of possible values is given, by the inputs fmin and fmax.
2nd col: The total reads of the CpG in the corresponding location.
3rd col: The methylated reads of the CpG in the corresponding location.
prom_region: A GRanges object
containing corresponding annotated promoter regions for each entry of the
methyl_region list..
rna_data: A GRanges object
containing the corresponding RNA-Seq data for each entry of the
methyl_region list. 
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