assaron/BioNet: Routines for the functional analysis of biological networks

This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. E.g. p-values obtained from the differential expression of the genes from an Affymetrix array are assigned to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from the p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork.

Getting started

Package details

AuthorMarcus Dittrich and Daniela Beisser
Bioconductor views DataImport DifferentialExpression GeneExpression GraphAndNetwork Microarray Network NetworkEnrichment
MaintainerMarcus Dittrich <>
LicenseGPL (>= 2)
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
assaron/BioNet documentation built on Sept. 18, 2020, 12:02 a.m.