This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. E.g. p-values obtained from the differential expression of the genes from an Affymetrix array are assigned to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from the p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork.
|Author||Marcus Dittrich and Daniela Beisser|
|Bioconductor views||DataImport DifferentialExpression GeneExpression GraphAndNetwork Microarray Network NetworkEnrichment|
|Maintainer||Marcus Dittrich <email@example.com>|
|License||GPL (>= 2)|
|Package repository||View on GitHub|
Install the latest version of this package by entering the following in R:
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.