Compartmap performs direct inference of higher-order chromatin from scRNA-seq and scATAC-seq. This package implements a James-Stein estimator for computing single-cell level higher-order chromatin domains. Further, we utilize random matrix theory as a method to de-noise correlation matrices to achieve a similar "plaid-like" patterning as observed in Hi-C and scHi-C data.
|Bioconductor views||ATACSeq Epigenetics Genetics RNASeq SingleCell|
|License||GPL-3 + file LICENSE|
|Package repository||View on GitHub|
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