calculate_trans_rate_sigurdson: Calculate Sigurdson's translocation rate

In biodosimetry-uab/biodosetools: An R Shiny Application for Biological Dosimetry

Calculate Sigurdson's translocation rate

Description

Method based on the paper by Sigurdson, A. J. et al. (2008). International study of factors affecting human chromosome translocations. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 652(2), 112-121. <doi:10.1016/j.mrgentox.2008.01.005>.

Usage

calculate_trans_rate_sigurdson(
  cells,
  genome_factor,
  age_value,
  sex_bool = FALSE,
  sex_value = "none",
  smoker_bool = FALSE,
  ethnicity_value = "none",
  region_value = "none"
)

Arguments

cells	Number of cells N.
genome_factor	Genomic conversion factor.
age_value	Age of the individual.
sex_bool	If TRUE, sex_value will be used.
sex_value	Sex of the individual, either "male" of "female".
smoker_bool	Whether the individual smokes or not.
ethnicity_value	Ethnicity of the individual.
region_value	Region of the individual.

Value

Numeric value of translocation rate.

biodosimetry-uab/biodosetools documentation built on Jan. 26, 2024, 5:36 p.m.