estimate_hetero_mixed_poisson: Heterogeneous dose estimation (Mixed Poisson model)

In biodosimetry-uab/biodosetools: An R Shiny Application for Biological Dosimetry

Heterogeneous dose estimation (Mixed Poisson model)

Description

Method based on the paper by Pujol, M. et al. (2016). A New Model for Biological Dose Assessment in Cases of Heterogeneous Exposures to Ionizing Radiation. Radiation Research, 185(2), 151-162. <doi:10.1667/RR14145.1>.

Usage

estimate_hetero_mixed_poisson(
  case_data,
  fit_coeffs,
  fit_var_cov_mat,
  conf_int = 0.95,
  protracted_g_value = 1,
  gamma,
  gamma_error
)

Arguments

case_data	Case data in data frame form.
fit_coeffs	Fitting coefficients matrix.
fit_var_cov_mat	Fitting variance-covariance matrix.
conf_int	Confidence interval, 95% by default.
protracted_g_value	Protracted G(x) value.
gamma	Survival coefficient of irradiated cells.
gamma_error	Error of the survival coefficient of irradiated cells.

Value

List containing estimated mixing proportions data frame, estimated yields data frame, estimated doses data frame, estimated fraction of irradiated blood data frame, AIC, and conf_int_* used.

biodosimetry-uab/biodosetools documentation built on Nov. 28, 2024, 10:12 a.m.