estimate_partial_body_dolphin: Partial-body dose estimation (Dolphin's method)

In biodosimetry-uab/biodosetools: An R Shiny Application for Biological Dosimetry

Partial-body dose estimation (Dolphin's method)

Description

Method based on the paper by Dolphin, G. W. (1969). Biological Dosimetry with Particular Reference to Chromosome Aberration Analysis: A Review of Methods. International Atomic Energy Agency (IAEA) Retrieved from https://inis.iaea.org/search/search.aspx?orig_q=RN:45029080.

Usage

estimate_partial_body_dolphin(
  case_data,
  fit_coeffs,
  fit_var_cov_mat,
  conf_int = 0.95,
  protracted_g_value = 1,
  genome_factor = 1,
  gamma,
  aberr_module = c("dicentrics", "translocations", "micronuclei")
)

Arguments

case_data	Case data in data frame form.
fit_coeffs	Fitting coefficients matrix.
fit_var_cov_mat	Fitting variance-covariance matrix.
conf_int	Confidence interval, 95% by default.
protracted_g_value	Protracted G(x) value.
genome_factor	Genomic conversion factor used in translocations, else 1.
gamma	Survival coefficient of irradiated cells.
aberr_module	Aberration module.

Value

List containing estimated doses data frame, observed fraction of cells scored which were irradiated, estimated fraction of irradiated blood data frame, AIC, and conf_int_* used.

biodosimetry-uab/biodosetools documentation built on Nov. 28, 2024, 10:12 a.m.