estimate_whole_body_merkle: Whole-body dose estimation (Merkle's method)

In biodosimetry-uab/biodosetools: An R Shiny Application for Biological Dosimetry

Whole-body dose estimation (Merkle's method)

Description

Method based on the paper by Merkle, W. (1983). Statistical methods in regression and calibration analysis of chromosome aberration data. Radiation and Environmental Biophysics, 21(3), 217-233. <doi:10.1007/BF01323412>.

Usage

estimate_whole_body_merkle(
  case_data,
  fit_coeffs,
  fit_var_cov_mat,
  conf_int_yield = 0.83,
  conf_int_curve = 0.83,
  protracted_g_value = 1,
  genome_factor = 1,
  aberr_module = c("dicentrics", "translocations", "micronuclei")
)

Arguments

case_data	Case data in data frame form.
fit_coeffs	Fitting coefficients matrix.
fit_var_cov_mat	Fitting variance-covariance matrix.
conf_int_yield	Confidence interval of the yield, 83% by default.
conf_int_curve	Confidence interval of the curve, 83% by default.
protracted_g_value	Protracted G(x) value.
genome_factor	Genomic conversion factor used in translocations, else 1.
aberr_module	Aberration module.

Value

List containing estimated doses data frame, AIC, and conf_int_* used.

biodosimetry-uab/biodosetools documentation built on Nov. 28, 2024, 10:12 a.m.