get_deltamethod_std_err: Get standard errors using delta method

In biodosimetry-uab/biodosetools: An R Shiny Application for Biological Dosimetry

Get standard errors using delta method

Description

Delta method for approximating the standard error of a transformation g(X) of a random variable X = (x1, x2, ...), given estimates of the mean and covariance matrix of X.

Usage

get_deltamethod_std_err(
  fit_is_lq,
  variable = c("dose", "fraction_partial", "fraction_hetero"),
  mean_estimate,
  cov_estimate,
  protracted_g_value = NA,
  d0 = NA
)

Arguments

fit_is_lq	Whether the fit is linear quadratic (TRUE) or linear (FALSE).
variable	Variable resulting of the transformation g(X).
mean_estimate	The estimated mean of X.
cov_estimate	The estimated covariance matrix of X.
protracted_g_value	Protracted G(x) value.
d0	Survival coefficient of irradiated cells.

Value

Numeric value containing the standard error of the dose estimate.

biodosimetry-uab/biodosetools documentation built on May 1, 2022, 11:22 p.m.