Man pages for bm2-lab/MASCOT
Model-based Understanding of SIngle-cell CRISPR screening
| Cell_filtering | Filtering perturbed cells with invalid edits. |
| Cell_qc | Quality control for single-cell CRISPR screening data. |
| Correlation_perturbation | Calculating the relationships between different... |
| cosin_dis_diffMatrix | parallel calculation for cosin similarity between two... |
| Data_imputation | Data imputation by SAVER. |
| Diff_perturb_effect | Calculating perturbation effect difference under different... |
| Diff_topic_distri | Calcualting topic distribution difference between case and... |
| Get_high_varGenes | Identify highly dispersion differentially expressed genes. |
| Get_offtarget | Evaluating the offtarget effect of sgRNAs. |
| Get_topics | Performing topic model to single-cell CRISPR screening data. |
| Input_preprocess | The preprocess of input data. |
| Input_preprocess_10X | The preprocess of input data generated with 10X genomics. |
| perturb_information_replace_name | Change the perturbation name. |
| Rank_overall | Calculating the overall perturbation effect ranking list. |
| Rank_specific | Calculating the topic-specific perturbation effect ranking... |
| Select_topic_number | To select the optimal topic number. |
| Topic_func_anno | Annotating each topic's function. |
