Rank_overall: Calculating the overall perturbation effect ranking list.

View source: R/MUSIC.r

Rank_overallR Documentation

Calculating the overall perturbation effect ranking list.

Description

MUSIC prioritizes the gene perturbation effect either as an overall perturbation effect on the cells, or in a functional topic-specific way. Here, the function calcultes and obtains the overall perturbation effect ranking list.

Usage

Rank_overall(distri_diff, offTarget_hash = hash(), output = FALSE, file_path = "./rank_overall.txt")

Arguments

distri_diff

A dataframe showing the topic distribution difference between case and control which can obtain from "Diff_topic_distri()" in this package.

offTarget_hash

A hash table showing offtarget information which can obtain from "Get_Offtarget()". The default is a null hash.

output

FALSE by default. If it is TRUE, then the result will be outputted to a file.

file_path

The save path of the result. It works only when the parameter "output" is TRUE.

Value

A dataframe, the overall perturbation effect ranking list.

Author(s)

Bin Duan


bm2-lab/MASCOT documentation built on April 19, 2024, 4:35 p.m.