Rank_specific: Calculating the topic-specific perturbation effect ranking...

In bm2-lab/MASCOT: Model-based Understanding of SIngle-cell CRISPR screening

Calculating the topic-specific perturbation effect ranking list.

Description

MUSIC prioritizes the gene perturbation effect either as an overall perturbation effect on the cells, or in a functional topic-specific way. Here, the function calcultes and obtains the topic-specific perturbation effect ranking list.

Usage

Rank_specific(distri_diff, output = FALSE, file_path = "./rank_specific.txt")

Arguments

distri_diff	A dataframe showing the topic distribution difference between case and control which can obtain from "Diff_topic_distri()" in this package.
output	FALSE by default. If it is TRUE, then the result will be outputted to a file.
file_path	The save path of the result. It works only when the parameter "output" is TRUE.

Value

A dataframe, the topic-specific perturbation effect ranking list

Author(s)

Bin Duan

bm2-lab/MASCOT documentation built on April 19, 2024, 4:35 p.m.