compare_Theta: Compute the differences between two Mutual Hazard Networks

In cbg-ethz/TreeMHN: Joint inference of repeated evolutionary trajectories and patterns of clonal exclusivity from single-cell mutation trees

Compute the differences between two Mutual Hazard Networks

Description

This function computes the differences between two Mutual Hazard Networks.

Usage

compare_Theta(true_Theta, pred_Theta, q = 0.01)

Arguments

true_Theta	A ground truth MHN represented by a square matrix.
pred_Theta	An estimated MHN represented by a square matrix.
q	A threshold to zero out very small entries in the estimated MHN (Default: 1e-2).

Value

A vector of performance metrics:

• SHD: Structural Hamming Distance between the two matrices;

• TP: True positives in the estimated MHN;

• FP: False positives in the estimated MHN;

• TN: True negatives in the estimated MHN;

• FN: False negatives in the estimated MHN;

• Precision: True positives divided by the total number of edges in the estimated MHN;

• TPR (Recall): True positives divided by the total number of edges in the true MHN;

• FPR_N: False positives divided by the total number of non-edges in the true MHN;

• FPR_P: False positives divided by the total number of edges in the true MHN;

• MSE: Mean squared error between the two matrices.

Author(s)

Xiang Ge Luo

cbg-ethz/TreeMHN documentation built on Jan. 29, 2024, 1:29 p.m.