pruneRegulon: Prune Regulons

In chrischen1/viper_copy: Virtual Inference of Protein-activity by Enriched Regulon analysis

Description

This function limits the maximum size of the regulons

Usage

pruneRegulon(regulon, cutoff = 50, eliminate = FALSE)

Arguments

regulon	Object of class regulon
cutoff	Number indicating the maximum size for the regulons (maximum number of target genes)
eliminate	Logical whether regulons smalles than cutoff should be eliminated

Value

Prunned regulon

See Also

viper, msviper

Examples

data(bcellViper, package="bcellViper")
hist(sapply(regulon, function(x) sum(x$likelihood)/max(x$likelihood)), nclass=20)
preg <- pruneRegulon(regulon, 400)
hist(sapply(preg, function(x) sum(x$likelihood)/max(x$likelihood)), nclass=20)

chrischen1/viper_copy documentation built on May 13, 2019, 6:52 p.m.