dengchunyu/scPagwas: A pathway-based polygenic integration method for inferring disease-associated individual cells in single cell sequencing data

scPagwas, a polygenic principal component-scoring method that links scRNA-seq data with large-scale GWAS summary statistics to prioritize genetics-modulated cells associated with complex diseases.scPagwas is able to prioritize disease-associated individual cells by integrating the scRNA-seq data with polygenic signals from GWAS.

install.packages("remotes")
remotes::install_github("dengchunyu/scPagwas")