createPPI: Create protein-protein interactions.

In edroaldo/fusca: Framework for Unified Single-Cell Analysis

Create protein-protein interactions.

Description

Create a protein-protein interaction network for the reconstruction of cell signaling pathways.

Usage

createPPI(filename, expr)

Arguments

filename	character; protein interaction data.
expr	dgCMatrix; gene expression in each cell, found in CellRouter@ndata.

Value

list; the network (igraph object), the ctable (data frame) with the edge list, the table (data frame) with the information of the ids of gene A and B and the scores, the genes in total (character vector), genesPPI (character vector) with the genes in the interactions, and the remove (character vector) with the genes not used in the interactions.

edroaldo/fusca documentation built on March 1, 2023, 1:43 p.m.