power.eqtl.simulated: Power calculation for an eQTL gene using simulations

In heiniglab/scPower: Experimental design framework for scRNAseq population studies (eQTL and DE)

Power calculation for an eQTL gene using simulations

Description

The eQTL power is independent of the mean except for very small mean values, where small effect sizes might not be detectable due to the discrete counts In these cases, the power can instead be simulated.

Usage

power.eqtl.simulated(
  count.mean,
  heritability,
  sig.level,
  nSamples,
  rep.times = 100
)

Arguments

count.mean	Expression mean in the pseudobulk
heritability	Heritability of the trait
sig.level	Significane threshold
nSamples	Sample size
rep.times	Number of repetitions used for the

Value

Power to detect the eQTL gene

heiniglab/scPower documentation built on Jan. 9, 2025, 12:13 p.m.