dataMLPA: MLPA data

In isglobal-brge/CNVassoc: Association analysis of CNVs and imputed SNPs incorporating uncertainty

Description

This data set contains data from a MLPA assay for a case-control study. The data has intensities for two genes that can be used to infer copy number status. It also contains the TRUE copy number status obtained by using PCR technology.

Usage

data(dataMLPA)

Format

dataMLPA is a data.frame with the following columns:

id	The unique identifiers of individuals
casco	Case-control stauts 0:control 1:case
Gene1	Intensities for Gene1
Gene2	Intensities for Gene2
PCR.Gene1	True copy number status for Gene1
PCR.Gene2	True copy number status for Gene2
quanti	Simulated continuos variable. It was generated to illustrate how to perform association analysis between a CNV and continuous traits
cov	Simulated continuous variable. It was generated to illustrate how to perform association adjusting for covariates

Value

A data frame with 651 rows and 8 columns.

Source

This data set was generated and kindly provided by Estivill's lab. The data is still unpublished and it has been made available in a blinded format for reproducing the findings presented in the paper

References

Gonzalez JR, Subirana I, Escaramis G, Peraza S, Caceres A, Estivill X and Armengol L. Accounting for uncertainty when assessing association between copy number and disease: a latent class model. BMC Bioinformatics, 2009;10:172.

Examples

data(dataMLPA)
head(dataMLPA)

isglobal-brge/CNVassoc documentation built on May 30, 2019, 9:48 p.m.