impute_normal: Impute missing values by random numbers drawn from a normal...

In jdreyf/jdcbioinfo: Joslin Diabetes Center bioinformatics utilities

Impute missing values by random numbers drawn from a normal distribution

Description

Impute missing values by random numbers drawn from a normal distribution that has a down-shifted mean and shrunken standard deviation from the sample distribution. This is meant to be similar to imputation in the Perseus software.

Usage

impute_normal(object, width = 0.3, downshift = 1.8, seed = 100)

Arguments

object	Data frame or matrix containing filtered and log-transformed data.
width	Scale factor for the standard deviation of imputed distribution relative to the sample standard deviation.
downshift	Down-shifted the mean of imputed distribution from the sample mean, in units of sample standard deviation.
seed	Random seed

Value

A matrix with imputed values

jdreyf/jdcbioinfo documentation built on April 15, 2024, 6:37 p.m.