multi_pval2z: Convert multiple columns of p-values to Z-scores

In jdreyf/jdcbioinfo: Joslin Diabetes Center bioinformatics utilities

Convert multiple columns of p-values to Z-scores

Description

Convert multiple columns (from a table-like object) of p-values from two-sided tests to Z-scores.

Usage

multi_pval2z(tab, prefix.v = NULL, p.suffix = "p", direction.suffix = "logFC")

Arguments

tab	Table of output from ezlimma.
prefix.v	A vector of prefixes that prefix .p, .FDR, or .logFC in colnames(tab). These will be the columns that are used in the Venn diagram. If NULL these are inferred from colnames(tab) that end with .p.
p.suffix	The suffix of p-value columns, i.e. the character string after the period "."
direction.suffix	The suffix of direction columns such as log fold-change, regression slope, correlation coefficient, or the "Up/Down" values

Details

P-values of zero are changed to half the lowest non-zero p-value and p-values of one are analogously changed, as p-values of zero or one would yield infinite z-scores.

Value

Matrix of Z-scores.

jdreyf/jdcbioinfo documentation built on Feb. 12, 2025, 4:30 p.m.