PPmarginal.multiple.fast.fn: Approximate (fast) marginal PP for models of a set of...

In jennasimit/MTFM: Multinomial fine-mapping

Description

Approximate (fast) marginal PP for models of a set of diseases, sharing information between the diseases

Usage

PPmarginal.multiple.fast.fn(SM2, dis, thr, kappa, fthr, N0, ND, nsnps)

Arguments

SM2	List of snpmod objects for a set of diseases
dis	Vector of diseases for fine-mapping (subset from those in SM2)
thr	Threshold such that the smallest set of models has cumulative PP >= thr
kappa	Vector of sharing values
fthr	Second level filtering on all but first disease to give a faster approximation; retain SNPs within the smallest set of models such that cumulative PP >= thr
N0	number of shared controls
ND	list of number of cases for a set of diseases
nsnps	Number of SNPs in region

Value

List consisting of PP: marginal PP for models and MPP: marginal PP of SNP inclusion

Author(s)

Jenn Asimit

jennasimit/MTFM documentation built on Aug. 15, 2019, 6:14 p.m.